Note: This is a home collection test kit that will be mailed to you.
Fasting Required: No
Special Instructions: Ship to lab Monday-Thursday only.
If you are taking antifungal or antibiotic medications, please finish the course of medication, and then wait three days before starting this collection. Please refrain from taking digestive enzymes, laxatives (particularly mineral oil and castor oil), antacids, aspirin, and substances containing barium and/or bismuth for two days prior to and during the specimen collection, unless otherwise instructed by your physician. Refrain from taking probiotic supplements for two weeks prior to specimen collection unless instructed otherwise by your physician. To properly assess fat absorption, be sure to consume normal amounts of dietary fat.
This is a 2 day stool collection. Specimen does not have to be collected on consecutive days. It is preferable, but not necessary, to collect on consecutive days but the final collection must be made within seven days of the first.
Please note: Parasites do not drop with every stool passing.
Results: 10-14 Business Days
The Comprehensive Stool Analysis is a noninvasive assessment of digestive and absorptive functions that includes digestion, absorption, bacterial balance, metabolism, inflammation, yeast and immune status for patients with nonspecific GI-related symptoms, such as indigestion, dysbiosis (microbial imbalance), constipation, and diarrhea, as well as the presence of adaptable pathogens and monitoring the usefulness of therapeutic treatment of Gastrointestinal (GI) disorders.
Important information regarding the efficiency of digestion and absorption can be gleaned from the measurement of the fecal levels of elastase (pancreatic exocrine sufficiency), fat, muscle and vegetable fibers, and carbohydrates.
Inflammation can significantly increase intestinal permeability and compromise assimilation of nutrients. The extent of inflammation, whether caused by pathogens or inflammatory bowel disease (IBD), can be assessed and monitored by examination of the levels of biomarkers such as lysozyme, lactoferrin, white blood cells and mucus. These markers can be used to differentiate between inflammation associated with potentially life-threatening inflammatory bowel disease (IBD), which requires lifelong treatment, and less severe inflammation that can be associated with irritable bowel syndrome (IBS) which is frequently due to the presence of enteroinvasive pathogens. Lactoferrin is only markedly elevated prior to and during the active phases of IBD, but not with IBS. Monitoring fecal lactoferrin levels in patients with IBD can therefore facilitate timely treatment of IBD, and the test can be ordered separately. Since the vast majority of secretory IgA (sIgA) is normally present in the GI tract, where it prevents binding of pathogens and antigens to the mucosal membrane, it is essential to know the status of sIgA in the gut. sIgA is the only bona fide marker of humoral immune status in the GI tract.
Cornerstones of good health include proper digestion of food, assimilation of nutrients, exclusion of pathogens and timely elimination of waste. To obtain benefits from food that is consumed, nutrients must be appropriately digested and then efficiently absorbed into portal circulation. Microbes, larger-sized particles of fiber, and undigested foodstuffs should remain within the intestinal lumen. Poor digestion and malabsorption of vital nutrients can contribute to degenerative diseases, compromised immune status and nutritional deficiencies. Impairment of the highly specific nutrient uptake processes, or compromised GI barrier function, as in “leaky gut syndrome,” can result from a number of causes including:
- Low gastric acid production
- Chronic maldigestion
- Food allergen impact on bowel absorptive surfaces
- Bacterial overgrowth or imbalances (dysbiosis)
- Pathogenic bacteria, yeast or parasites and related toxic irritants
- The use of NSAIDs and antibiotics
Impairment of intestinal functions can contribute to the development of food allergies, systemic illnesses, autoimmune disease, and toxic overload from substances that are usually kept in the confines of the bowel for elimination. Efficient remediation of GI dysfunctions incorporates a comprehensive guided approach that should include consideration of elimination of pathogens and exposure to irritants, supplementation of hydrochloric acid, pancreatic enzymes and pre- and probiotics, and repair of the mucosal barrier.
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.