PSA (Prostate Specific Antigen)
Fasting Required: No

Specimen: Blood

Results: 3-6 Business Days

Description:
The prostate specific antigen (PSA), is a protein made only in the prostate gland. PSA is produced by normal, abnormal and cancerous prostatic tissue. The PSA blood test is an accurate measure of this amount. The theory is that cancer causes more of the protein to be made and leaked into the blood than normal prostate tissue, so PSA is now used for assisting in the diagnosis and monitoring of prostatic carcinoma.

Methodology:
Immunoassay

Limitations:
Based on solid evidence, screening with PSA and/or DRE detects some prostate cancers that would never have caused important clinical problems. Current prostate cancer treatments, including radical prostatectomy and radiation therapy, result in permanent side effects in many men. The most common of these side effects are erectile dystunction and urinary incontinence. Whatever the screening modality, the screening process itself can lead to adverse psychological effects in men who have a prostate biopsy but do not have identified prostate cancer. Prostatic biopsies are associated with complications, including fever, pain, hematospermia/hematuria, positive urine cultures, and rarely sepsis. Lower PSA levels are associated with obesity.

Reference Range(s):
=4.0 ng/mL

Clinical Significance:
Elevated serum PSA concentrations have been reported in men with prostate cancer, benign prostatic hypertrophy, and inflammatory conditions of the prostate.

Alternative Name(s):
PSA, Total

Note: Result turn around times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

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